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1

Molecular imaging strategies for drug discovery and development

Shimon Gross, David Piwnica-Worms

Journal:

Current Opinion in Chemical Biology

Année:

2006

Langue:

english

Fichier:

PDF, 395 KB

english, 2006

2

Use of an oriented peptide library to determine the optimal substrates of protein kinases

Zhou Songyang, Steven Blechner, Nicole Hoagland, Merl F. Hoekstra, Helen Piwnica-Worms, Lewis C. Cantley

Journal:

Current Biology

Année:

1994

Langue:

english

Fichier:

PDF, 1.38 MB

english, 1994

3

Targeting Tumor-Infiltrating Macrophages Decreases Tumor-Initiating Cells, Relieves Immunosuppression, and Improves Chemotherapeutic Responses

Mitchem, J. B., Brennan, D. J., Knolhoff, B. L., Belt, B. A., Zhu, Y., Sanford, D. E., Belaygorod, L., Carpenter, D., Collins, L., Piwnica-Worms, D., Hewitt, S., Udupi, G. M., Gallagher, W. M., Wegner

Journal:

Cancer Research

Année:

2013

Langue:

english

Fichier:

PDF, 3.77 MB

english, 2013

4

TAT-Bim Induces Extensive Apoptosis in Cancer Cells

Hiroyuki Kashiwagi, Jonathan E. McDunn, Peter S. Goedegebuure, Mary C. Gaffney, Katherine Chang, Kathryn Trinkaus, David Piwnica-Worms, Richard S. Hotchkiss, William G. Hawkins

Journal:

Annals of Surgical Oncology

Année:

2007

Langue:

english

Fichier:

PDF, 466 KB

english, 2007

5

Disruption of the checkpoint kinase 1/cell division cycle 25A pathway abrogates ionizing radiation-induced S and G2 checkpoints

Zhao, H., Watkins, J. L., Piwnica-Worms, H.

Journal:

Proceedings of the National Academy of Sciences

Année:

2002

Langue:

english

Fichier:

PDF, 248 KB

english, 2002

6

Microtubule affinity-regulating kinase 2 functions downstream of the PAR-3/PAR-6/atypical PKC complex in regulating hippocampal neuronal polarity

Chen, Y. M., Wang, Q. J., Hu, H. S., Yu, P. C., Zhu, J., Drewes, G., Piwnica-Worms, H., Luo, Z. G.

Journal:

Proceedings of the National Academy of Sciences

Année:

2006

Langue:

english

Fichier:

PDF, 3.58 MB

english, 2006

7

Book Review MRI: Central nervous system Edited by Walter Kucharczyk. Approximately 300 pp., illustrated. Philadelphia, J.B. Lippincott/Gower Medical, 1990. $79.50. MRI: Musculoskeletal system Edited by Javier Beltran. Approximately 325 pp., illustrated. Philadelphia, J.B. Lippincott/Gower Medical, 1990. $79.50.

Piwnica-Worms, David, Jolesz, Ferenc

Journal:

Boston Medical and Surgical Journal

Année:

1991

Fichier:

PDF, 421 KB

1991

8

Cyclin A/CDK2 binds directly to E2F-1 and inhibits the DNA-binding activity of E2F-1/DP-1 by phosphorylation.

Xu, M, Sheppard, K A, Peng, C Y, Yee, A S, Piwnica-Worms, H

Journal:

Molecular and Cellular Biology

Année:

1994

Langue:

english

Fichier:

PDF, 3.38 MB

english, 1994

9

Mechanisms of p34cdc2 regulation.

Atherton-Fessler, S, Parker, L L, Geahlen, R L, Piwnica-Worms, H

Journal:

Molecular and Cellular Biology

Année:

1993

Langue:

english

Fichier:

PDF, 2.51 MB

english, 1993

10

MR Imaging of Septic Sacroiliitis

Klein, Mitchell A., Winalski, Carl S., Wax, Mark R., Piwnica-Worms, David R.

Journal:

Journal of Computer Assisted Tomography

Année:

1991

Fichier:

PDF, 825 KB

1991

11

Spatial and Temporal Confined Photothermolysis of Cancer Cells Mediated by Hollow Gold Nanospheres Targeted to Epidermal Growth Factor Receptors

Ku, Geng, Huang, Qian, Wen, Xiaoxia, Ye, John, Piwnica-Worms, David, Li, Chun

Journal:

Année:

2018

Langue:

english

Fichier:

PDF, 9.87 MB

english, 2018

12

A comprehensive overview of metaplastic breast cancer: clinical features and molecular aberrations

Reddy, Tejaswini P., Rosato, Roberto R., Li, Xiaoxian, Moulder, Stacy, Piwnica-Worms, Helen, Chang, Jenny C.

Journal:

Breast Cancer Research

Année:

2020

Fichier:

PDF, 797 KB

2020

13

Fibrocystic disease of liver and pancreas; under-recognized features of the X-linked ciliopathy oral-facial-digital syndrome type 1 (OFD I)

Shilpa Chetty-John, Katie Piwnica-Worms, Joy Bryant, Isa Bernardini, Roxanne E. Fischer, Theo Heller, William A. Gahl, Meral Gunay-Aygun

Journal:

American Journal of Medical Genetics Part A

Année:

2010

Langue:

english

Fichier:

PDF, 201 KB

english, 2010

14

Squaraine Rotaxanes: Superior Substitutes for Cy-5 in Molecular Probes for Near-Infrared Fluorescence Cell Imaging

James R. Johnson, Na Fu, Easwaran Arunkumar, W. Matthew Leevy, Seth T. Gammon, David Piwnica-Worms, Bradley D. Smith

Journal:

Angewandte Chemie

Année:

2007

Langue:

english

Fichier:

PDF, 203 KB

english, 2007

15

Squaraine Rotaxanes: Superior Substitutes for Cy-5 in Molecular Probes for Near-Infrared Fluorescence Cell Imaging

James R. Johnson, Na Fu, Easwaran Arunkumar, W. Matthew Leevy, Seth T. Gammon, David Piwnica-Worms, Bradley D. Smith

Journal:

Angewandte Chemie International Edition

Année:

2007

Langue:

english

Fichier:

PDF, 204 KB

english, 2007

16

Rational design of novel red-shifted BRET pairs: Platforms for real-time single-chain protease biosensors

Seth T. Gammon, Victor M. Villalobos, Mikhail Roshal, Mustapha Samrakandi, David Piwnica-Worms

Journal:

Biotechnology Progress

Année:

2009

Langue:

english

Fichier:

PDF, 998 KB

english, 2009

17

ChemInform Abstract: Structure of a Novel Antimalarial Gallium(III) Complex with Selective Activity Against Chloroquine-Resistant Plasmodium falciparum

V. SHARMA, A. BEATTY, D. E. GOLDBERG, D. PIWNICA-WORMS

Journal:

Année:

1998

Fichier:

PDF, 28 KB

1998

18

ChemInform Abstract: Metal Complexes for Therapy and Diagnosis of Drug Resistance

Vijay Sharma, David Piwnica-Worms

Journal:

Année:

1999

Fichier:

PDF, 25 KB

1999

19

APT102, a novel adpase, cooperates with aspirin to disrupt bone metastasis in mice

Özge Uluçkan, Mark C. Eagleton, Desiree H. Floyd, Elizabeth A. Morgan, Angela C. Hirbe, Matthew Kramer, Nikki Dowland, Julie L. Prior, David Piwnica-Worms, Soon Seog Jeong, Ridong Chen, Katherine Weil

Journal:

Journal of Cellular Biochemistry

Année:

2008

Langue:

english

Fichier:

PDF, 667 KB

english, 2008

20

Molecular imaging of gene expression and protein function in vivo with PET and SPECT

Vijay Sharma, Gary D. Luker, David Piwnica-Worms

Journal:

Journal of Magnetic Resonance Imaging

Année:

2002

Langue:

english

Fichier:

PDF, 808 KB

english, 2002

21

Superparamagnetic Iron Oxide Hepatic MR Imaging: Efficacy and Safety Using Conventional and Fast Spin-Echo Pulse Sequences

Lawrence H. Schwartz, Steven E. Seltzer, Clare M. C. Tempany, Stuart G. Silverman, David R. Piwnica-Worms, Douglass F. Adams, Lee Herman, Lisa A. Herman, Roshann Hooshmand

Journal:

Journal of Magnetic Resonance Imaging

Année:

1995

Langue:

english

Fichier:

PDF, 628 KB

english, 1995

22

Intracellular water specific MR of microbead-adherent cells: Hela cell intracellular water diffusion

L. Zhao, A. L. Sukstanskii, C. D. Kroenke, J. Song, D. Piwnica-Worms, J. J. H. Ackerman, J. J. Neil

Journal:

Magnetic Resonance in Medicine

Année:

2008

Langue:

english

Fichier:

PDF, 115 KB

english, 2008

23

Intracellular water-specific MR of microbead-adherent cells: the HeLa cell intracellular water exchange lifetime

L. Zhao, C. D. Kroenke, J. Song, D. Piwnica-Worms, J. J. H. Ackerman, J. J. Neil

Journal:

NMR in Biomedicine

Année:

2008

Langue:

english

Fichier:

PDF, 128 KB

english, 2008

24

Mitochondrial localization and characterization of 99Tc-SESTAMIBI in heart cells by electron probe X-ray microanalysis and 99Tc-NMR spectroscopy

David Piwnica-Worms, James F. Kronauge, Ann LeFurgey, Mark Backus, Daniel Hockett, Peter Ingram, Melvyn Lieberman, B. Leonard Holman, Alun G. Jones, Alan Davison

Journal:

Magnetic Resonance Imaging

Année:

1994

Langue:

english

Fichier:

PDF, 3.07 MB

english, 1994

25

A method for quantification of nucleotides and nucleotide analogues in thymidine kinase assays using lanthanum phosphate coprecipitation

S.T. Gammon, M. Bernstein, D.P. Schuster, D. Piwnica-Worms

Journal:

Analytical Biochemistry

Année:

2007

Langue:

english

Fichier:

PDF, 250 KB

english, 2007

26

Dual-Color Click Beetle Luciferase Heteroprotein Fragment Complementation Assays

Victor Villalobos, Snehal Naik, Monique Bruinsma, Robin S. Dothager, Mei-Hsiu Pan, Mustapha Samrakandi, Britney Moss, Adnan Elhammali, David Piwnica-Worms

Journal:

Chemistry & Biology

Année:

2010

Langue:

english

Fichier:

PDF, 1.11 MB

english, 2010

27

Advances in bioluminescence imaging of live animal models

Robin S Dothager, Kelly Flentie, Britney Moss, Mei-Hsiu Pan, Aparna Kesarwala, David Piwnica-Worms

Journal:

Current Opinion in Biotechnology

Année:

2009

Langue:

english

Fichier:

PDF, 1.99 MB

english, 2009

28

Disruption of GBM - Endothelial Cell Interactions Through Antagonism of CXCR4 Signaling Inhibits Tumor Cell Growth

Rao, S.R., Woerner, M., Choe, A., Piwnica-Worms, D., Leonard, J., Simpson, J.R., Rubin, J.B.

Journal:

International Journal of Radiation Oncology*Biology*Physics

Année:

2009

Langue:

english

Fichier:

PDF, 39 KB

english, 2009

29

Synthesis, characterization, and molecular structure of a gallium(III) complex of an amine-phenol ligand with activity against chloroquine-sensitive Plasmodium falciparum strains

Joseph A. Ocheskey, Valery R. Polyakov, Scott E. Harpstrite, Anna Oksman, Daniel E. Goldberg, David Piwnica-Worms, Vijay Sharma

Journal:

Journal of Inorganic Biochemistry

Année:

2003

Langue:

english

Fichier:

PDF, 218 KB

english, 2003

30

Novel gallium(III) complexes transported by MDR1 P-glycoprotein: potential PET imaging agents for probing P-glycoprotein-mediated transport activity in vivo

V Sharma, A Beatty, S-P Wey, J Dahlheimer, CM Pica, CL Crankshaw, L Bass, MA Green, MJ Welch, D Piwnica-Worms

Journal:

Chemistry & Biology

Année:

2000

Langue:

english

Fichier:

PDF, 195 KB

english, 2000

31

Identification of protein phosphorylation sites within Ser/Thr-rich cluster domains using site-directed mutagenesis and hybrid linear quadrupole ion trap Fourier transform ion cyclotron resonance mass spectrometry

Julie B. King, Julia Gross, Christine M. Lovly, Helen Piwnica-Worms, R. Reid Townsend

Journal:

Rapid Communications in Mass Spectrometry

Année:

2007

Langue:

english

Fichier:

PDF, 205 KB

english, 2007

32

Interaction of (Na + K + 2 Cl) cotransport and the Na/K pump in cultured chick cardiac myocytes

Shi Liu, Ron Jacob, David Piwnica-Worms, Melvyn Lieberman

Journal:

Molecular and Cellular Biochemistry

Année:

1989

Langue:

english

Fichier:

PDF, 292 KB

english, 1989

33

Detection of Adriamycin-induced cardiotoxicity in cultured heart cells with technetium 99m-SESTAMIBI

David Piwnica-Worms, Mary L. Chiu, James F. Kronauge

Journal:

Cancer Chemotherapy and Pharmacology

Année:

1993

Langue:

english

Fichier:

PDF, 856 KB

english, 1993

34

Technoreview: Molecular imaging of host–pathogen interactions in intact small animals

David Piwnica-Worms, Daniel P. Schuster, Joel R. Garbow

Journal:

Cellular Microbiology

Année:

2004

Langue:

english

Fichier:

PDF, 391 KB

english, 2004

35

10.1038/26766

Piwnica-Worms, Helen, Zeng, Yan, Forbes, Kristi Chrispell, Wu, Zhiqi, Moreno, Sergio, Enoch, Tamar

Journal:

Année:

1998

Langue:

english

Fichier:

PDF, 368 KB

english, 1998

36

Human cdc2 protein kinase is a major cell-cycle regulated tyrosine kinase substrate

Draetta, Giulio, Piwnica-Worms, Helen, Morrison, Deborah, Druker, Brian, Roberts, Thomas, Beach, David

Journal:

Année:

1988

Fichier:

PDF, 892 KB

1988

37

Phosphorylation and inactivation of the mitotic inhibitor Weel by the nim1/cdr1 kinase

Parker, Laura L., Walter, Sarah A., Young, Paul G., Piwnica-Worms, Helen

Journal:

Année:

1993

Fichier:

PDF, 438 KB

1993

38

10.1038/44029

Piwnica-Worms, Helen

Journal:

Année:

1999

Langue:

english

Fichier:

PDF, 112 KB

english, 1999

39

PET imaging of heat-inducible suicide gene expression in mice bearing head and neck squamous cell carcinoma xenografts

Parry, J J, Sharma, V, Andrews, R, Moros, E G, Piwnica-Worms, D, Rogers, B E

Journal:

Cancer Gene Therapy

Année:

2008

Langue:

english

Fichier:

PDF, 240 KB

english, 2008

40

Dual phosphorylation controls Cdc25 phosphatases and mitotic entry

Bulavin, Dmitry V., Higashimoto, Yuichiro, Demidenko, Zoya N., Meek, Sarah, Graves, Paul, Phillips, Crissy, Zhao, Hui, Moody, Sally A., Appella, Ettore, Piwnica-Worms, Helen

Journal:

Nature Cell Biology

Année:

2003

Langue:

english

Fichier:

PDF, 685 KB

english, 2003

41

Bioluminescence imaging of myeloperoxidase activity in vivo

Gross, Shimon, Gammon, Seth T, Moss, Britney L, Rauch, Daniel, Harding, John, Heinecke, Jay W, Ratner, Lee, Piwnica-Worms, David

Journal:

Nature Medicine

Année:

2009

Langue:

english

Fichier:

PDF, 648 KB

english, 2009

42

Imaging 26S proteasome activity and inhibition in living mice

Luker, Gary D, Pica, Christina M, Song, Jiling, Luker, Kathryn E, Piwnica-Worms, David

Journal:

Nature Medicine

Année:

2003

Langue:

english

Fichier:

PDF, 343 KB

english, 2003

43

Real-time imaging of ligand-induced IKK activation in intact cells and in living mice

Gross, Shimon, Piwnica-Worms, David

Journal:

Année:

2005

Langue:

english

Fichier:

PDF, 667 KB

english, 2005

44

Identification of FUSE-binding protein 1 as a regulatory mRNA-binding protein that represses nucleophosmin translation

Olanich, M E, Moss, B L, Piwnica-Worms, D, Townsend, R R, Weber, J D

Journal:

Année:

2010

Langue:

english

Fichier:

PDF, 701 KB

english, 2010

45

Casein kinase 1 functions as both penultimate and ultimate kinase in regulating Cdc25A destruction

Honaker, Y, Piwnica-Worms, H

Journal:

Année:

2010

Langue:

english

Fichier:

PDF, 818 KB

english, 2010

46

Characterization of functional assays of multidrug resistance P-glycoprotein transport activity

Bosch, I, Crankshaw, C L, Piwnica-Worms, D, Croop, J M

Journal:

Année:

1997

Langue:

english

Fichier:

PDF, 308 KB

english, 1997

47

Localization of human Cdc25C is regulated both by nuclear export and 14-3-3 protein binding

Graves, Paul R, Lovly, Christine M, Uy, Geoffrey L, Piwnica-Worms, Helen

Journal:

Année:

2001

Langue:

english

Fichier:

PDF, 1.08 MB

english, 2001

48

Transglutaminase 2 inhibitor, KCC009, disrupts fibronectin assembly in the extracellular matrix and sensitizes orthotopic glioblastomas to chemotherapy

Yuan, L, Siegel, M, Choi, K, Khosla, C, Miller, C R, Jackson, E N, Piwnica-Worms, D, Rich, K M

Journal:

Année:

2006

Langue:

english

Fichier:

PDF, 471 KB

english, 2006

49

Chromatin Remodeling Underlies the Senescence-Associated Secretory Phenotype of Tumor Stromal Fibroblasts That Supports Cancer Progression

Pazolli, E., Alspach, E., Milczarek, A., Prior, J., Piwnica-Worms, D., Stewart, S. A.

Journal:

Cancer Research

Année:

2012

Langue:

english

Fichier:

PDF, 941 KB

english, 2012

50

Synthetic lethality of Chk1 inhibition combined with p53 and/or p21 loss during a DNA damage response in normal and tumor cells

Origanti, S, Cai, S-r, Munir, A Z, White, L S, Piwnica-Worms, H

Journal:

Année:

2013

Langue:

english

Fichier:

PDF, 943 KB

english, 2013